Physalin A
Product Specifications
CAS Number
23027-91-0
Target
JAK|||Autophagy|||STAT|||mTOR|||Apoptosis|||p38 MAPK|||Akt|||NF-?B|||PI3K
Related Pathways
NF-?B|||Tyrosine Kinase/Adaptors|||Autophagy|||Angiogenesis|||Chromatin/Epigenetic|||Stem Cells|||MAPK|||Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling|||Apoptosis|||JAK/STAT signaling
Purity
0.9971
Bioactivity
Physalin A is an anti-inflammatory compound isolated from P. alkekengi with anti-fibrotic effects, regulating the Nrf2 pathway through ERK and p38 to induce detoxification enzymes. Physalin A blocks the activation of the NF-kappaB signaling pathway. Physalin A reduces mammosphere formation by reducing the expression of the GLI1 gene and the YAP1 gene.
Smiles
C[C@@]12[C@]34[C@]([C@]5(C)C[C@]1(OC(=O)C5=C)[H])(C(=O)[C@](O)(O3)[C@]6([C@](CC[C@]4(O)C(=O)O2)([C@]7(C)C(=C[C@H]6O)CC=CC7=O)[H])[H])[H]
Molecular Formula
C28H30O10
Molecular Weight
526.53
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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