Nyasol
Product Specifications
CAS Number
96895-25-9
Target
Antifungal|||ERK|||Antifection|||Parasite|||IL Receptor|||NOS|||I?B/IKK|||Leukotriene Receptor|||Akt|||NF-?B|||NO Synthase|||Antibacterial
Related Pathways
PI3K/Akt/mTOR signaling|||Cytoskeletal Signaling|||Microbiology/Virology|||MAPK|||GPCR/G Protein|||Immunology/Inflammation|||NF-?B
Bioactivity
Nyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. Nyasol shows anti-inflammatory properties by inhibiting iNOS expression; it also has antifungal activity, it is significantly effective in suppressing the Phytophthora blight on pepper plants. (-) -Nyasol exhibits the half maximal inhibitory concentration (IC50) value of 17.6 uM against D-glycero-?-D-manno-heptose-1-phosphate guanylyltransferase (HddC) . (+) -Nyasol has antiprotozoal activity, it potently inhibits the growth of Leishmania major promastigotes, the IC50 being 12 microM, and moderately inhibits Plasmodium falciparum schizonts with the IC50 49 microM.
Smiles
Oc1ccc(cc1)\C=C/[C@@H](C=C)c1ccc(O)cc1
Molecular Formula
C17H16O2
Molecular Weight
252.31
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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