Niazimicin
Product Specifications
CAS Number
147821-49-6
Target
NF-κB, AChR, Antifection, PI3K
Related Pathways
PI3K/Akt/mTOR signaling, Neuroscience, Microbiology/Virology, NF-κB
Bioactivity
Niazimicin are NF-B and PI3K inhibitors, which shows antimicrobial, hypotensive and spasmolytic activities. Niazimicin has potent antitumor promoting activity in the two-stage carcinogenesis in mouse skin using 7,12-dimethylbenz (a) anthracene (DMBA) as initiator and TPA as tumor promoter, it is proposed to be a potent chemo-preventive agent.
Smiles
CCOC(=S)NCc1ccc(O[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)cc1
Molecular Formula
C16H23NO6S
Molecular Weight
357.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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