Nantenine
Product Specifications
CAS Number
2565-01-7
Target
Others, 5-HT Receptor
Related Pathways
Neuroscience, GPCR/G Protein, Others
Bioactivity
Nantenine is an acetylcholinesterase inhibitor, it functions as an effective antagonist against a wide range of MDMA-induced effects in mice. Nantenine has anticonvulsant effect, which seems attributable to its stimulation and the resultant decrease of Ca2+-influx into the cell. (+) -Nantenine has antagonistic activities on alpha1-adrenoceptors, alpha2-adrenoceptors and 5-HT2A receptors in pithed rats. Nantenine displays cytotoxicity against SMMC-7721 with the IC50 value of 70.08 ± 4.63 uM.
Smiles
COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23
Molecular Formula
C20H21NO4
Molecular Weight
339.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Frequently Asked Questions
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