Myricanone
Product Specifications
CAS Number
32492-74-3
Target
HSP, Bcl-2 Family, NF-κB, Caspase, STAT, ROS, Endogenous Metabolite
Related Pathways
NF-κB, Immunology/Inflammation, Cytoskeletal Signaling, Proteases/Proteasome, Stem Cells, JAK/STAT signaling, Metabolism, Apoptosis
Bioactivity
Myricanone has antioxidant, and anticancer activities, it has apoptosis-promoting ability by triggering caspase activation, and suppression of cell proliferation by down-regulation of NF-ÎoB and STAT3 signalling cascades. Myricanone shows in vitro testosterone 5alpha-reductase inhibitory activity and in vivo anti-androgenic activity using growth of flank organ in castrated Syrian hamsters and/or hair regrowth after shaving in testosterone-treated C57Black/6CrSlc mice.
Smiles
COc1c(O)c2CCCCC(=O)CCc3ccc(O)c(c3)-c(c2)c1OC
Molecular Formula
C21H24O5
Molecular Weight
356.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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