Moronic acid
Product Specifications
CAS Number
6713-27-5
Target
Antifection, HSV, NOD-like Receptor (NLR), HIV Protease, ROS
Related Pathways
Microbiology/Virology, Immunology/Inflammation, Proteases/Proteasome
Bioactivity
Moronic acid shows oral therapeutic efficacy in HSV-infected mice and possessed novel anti-HSV activity. It also shows significant anti-HIV activity (EC (50) 186) and was modified to develop more potent anti-AIDS agents. Moronic acid is a new structural lead for anti-EBV drug development, can substantially reduce the numbers of EBV particles produced by the cells after lytic induction. Morolic and moronic acids have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent changes of glucose, cholesterol and triglycerides, in part mediated by inhibition of 11β-HSD 1 as indicated by in vitro.
Smiles
CC1(C)CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CCC(=O)C(C)(C)[C@@H]5CC[C@@]34C)C2=C1)C(O)=O
Molecular Formula
C30H46O3
Molecular Weight
454.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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