Tectoquinone

Tectoquinone (2-Methylanthraquinone) is an inhibitor for SARS CoV-2 major protease (SARS CoV-2 Mpro) . Tectoquinone exhibits anti-termite and antiviral activities[1][2].

Product Specifications

CAS Number

[84-54-8]

Product Name Alternative

2-Methylanthraquinone

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

DNA Alkylator/Crosslinker; Insecticide; SARS-CoV; Virus Protease

Type

Natural Products

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Others

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/tectoquinone.html

Concentration

10mM

Purity

99.93

Solubility

DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1C2=C(C=CC=C2)C(C3=CC=C(C)C=C13)=O

Molecular Formula

C15H10O2

Molecular Weight

222.24

Precautions

H302, H315, H319, H335

References & Citations

[1]Sen-Sung Cheng, et al. Larvicidal activity of tectoquinone isolated from red heartwood-type Cryptomeria japonica against two mosquito species. Bioresour Technol. 2008 Jun;99 (9) :3617-22.|[2]Anoop Kallingal, et al. Molecular modeling study of tectoquinone and acteoside from Tectona grandis linn: a new SARS-CoV-2 main protease inhibitor against COVID-19. J Biomol Struct Dyn. 2022 Mar;40 (4) :1764-1775.|[3]Lin TS, et al., 2-Methylanthraquinone derivatives as potential bioreductive alkylating agents. J Med Chem. 1980 Nov;23 (11) :1237-42.