Jolkinolide A

Product Specifications

CAS Number

37905-07-0

Target

STAT|||mTOR|||VEGFR|||Akt|||Apoptosis

Related Pathways

Stem Cells|||PI3K/Akt/mTOR signaling|||Angiogenesis|||Apoptosis|||JAK/STAT signaling|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors

Bioactivity

Jolkinolide A has anti-tumor activity. It inhibited VEGF expression in A549 cells through the inhibition of the Akt-STAT3-mTOR signaling pathway, and directly inhibited the proliferation and migration of HUVECs.

Smiles

CC1=C2[C@H]3O[C@]33CC[C@@H]4C(C)(C)CCC[C@@]4(C)[C@@H]3C=C2OC1=O

Molecular Formula

C20H26O3

Molecular Weight

314.42

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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