Jolkinolide A
Product Specifications
CAS Number
37905-07-0
Target
STAT|||mTOR|||VEGFR|||Akt|||Apoptosis
Related Pathways
Stem Cells|||PI3K/Akt/mTOR signaling|||Angiogenesis|||Apoptosis|||JAK/STAT signaling|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors
Bioactivity
Jolkinolide A has anti-tumor activity. It inhibited VEGF expression in A549 cells through the inhibition of the Akt-STAT3-mTOR signaling pathway, and directly inhibited the proliferation and migration of HUVECs.
Smiles
CC1=C2[C@H]3O[C@]33CC[C@@H]4C(C)(C)CCC[C@@]4(C)[C@@H]3C=C2OC1=O
Molecular Formula
C20H26O3
Molecular Weight
314.42
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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