Isojacareubin
Product Specifications
CAS Number
50597-93-8
Target
PKC, Apoptosis, Antifection, MAPK, SARS-CoV, Antibacterial
Related Pathways
Chromatin/Epigenetic, Apoptosis, MAPK, Cytoskeletal Signaling, Microbiology/Virology
Bioactivity
Isojacareubin displays potent activity against H. pylori HP40 clinical isolate with MIC 23.9 uM, which is approximately two times greater than that of the standard drug amoxicillin. Isojacareubin is a potent inhibitor of protein kinase C (PKC), suppresses hepatocellular carcinoma metastasis and induces apoptosis in vitro and in vivo, thus, it as a promising lead compound for the development of new antihepatoma agents.
Smiles
CC1(C)Oc2cc(O)c3c(oc4c(O)c(O)ccc4c3=O)c2C=C1 |c:25|
Molecular Formula
C18H14O6
Molecular Weight
326.304
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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