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Hedycoronen A

Product Specifications

CAS Number

1383441-73-3

Target

IL Receptor|||Interleukin|||TNF

Related Pathways

Immunology/Inflammation|||Apoptosis

Bioactivity

Hedycoronen A and hedycoronen B have the potential anti-inflammatory benefits, they are potent inhibitors of LPS-stimulated interleukin-6 (IL-6) and IL-12 p40, with IC (50) ranging from 4.1±0.2 to 9.1±0.3 uM, they also show moderate inhibitory activity on the tumor necrosis factor-? (TNF-?) production with IC (50) values of 46.0±1.3 and 12.7±0.3 uM.

Smiles

COC1OC(=O)C(=C1)\C=C\[C@H]1C(=C)CC[C@H]2C(C)(C)CCC[C@]12C

Molecular Formula

C21H30O3

Molecular Weight

330.46

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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