Griffipavixanthone
Product Specifications
CAS Number
219649-95-3
Target
ROS, Raf, ERK, MEK, Apoptosis, Caspase
Related Pathways
Proteases/Proteasome, Apoptosis, Immunology/Inflammation, MAPK
Bioactivity
Griffipavixanthone inhibits the growth of human Non-small-cell lung cancer H520 cells in dose- and time-dependent manners, it induces cell apoptosis through mitochondrial apoptotic pathway accompanying with ROS production. It can inhibit tumor metastasis and proliferation via downregulation of the RAF pathway in esophageal cancer.
Smiles
CC1=C[C@H]2[C@H]([C@@H](c3c2c2c(oc4cc(O)cc(O)c4c2=O)c(O)c3O)c2cc(O)c(O)c3oc4cc(O)cc(O)c4c(=O)c23)C(C)(C)C1
Molecular Formula
C36H28O12
Molecular Weight
652.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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