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Griffipavixanthone

Product Specifications

CAS Number

219649-95-3

Target

ROS, Raf, ERK, MEK, Apoptosis, Caspase

Related Pathways

Proteases/Proteasome, Apoptosis, Immunology/Inflammation, MAPK

Bioactivity

Griffipavixanthone inhibits the growth of human Non-small-cell lung cancer H520 cells in dose- and time-dependent manners, it induces cell apoptosis through mitochondrial apoptotic pathway accompanying with ROS production. It can inhibit tumor metastasis and proliferation via downregulation of the RAF pathway in esophageal cancer.

Smiles

CC1=C[C@H]2[C@H]([C@@H](c3c2c2c(oc4cc(O)cc(O)c4c2=O)c(O)c3O)c2cc(O)c(O)c3oc4cc(O)cc(O)c4c(=O)c23)C(C)(C)C1

Molecular Formula

C36H28O12

Molecular Weight

652.6

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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