What is the catalog number for Excisanin A?

The catalog number for Excisanin A is TN4046.

What sizes are available for Excisanin A?

Excisanin A is available in the following size(s): 1 mg, 5 mg.

How many pack sizes does Excisanin A come in?

Excisanin A is available in 2 different pack sizes.

Is Excisanin A in stock?

Excisanin A is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Excisanin A?

Excisanin A is manufactured by Molfinity.

What is the estimated delivery time for Excisanin A?

Estimated delivery time for Excisanin A is approximately 10 business day(s), depending on your location.

Excisanin A

Product Specifications

CAS Number

78536-37-5

Target

MMP, Integrin, Prostaglandin Receptor, FAK, JNK, GSK-3, Akt, Caspase, PARP, NF-κB, Src, PI3K, Wnt/beta-catenin

Related Pathways

PI3K/Akt/mTOR signaling, GPCR/G Protein, Stem Cells, NF-κB, MAPK, Apoptosis, Immunology/Inflammation, Angiogenesis, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Proteases/Proteasome, DNA Damage/DNA Repair, Cytoskeletal Signaling

Bioactivity

ExcisaninA may be a potent inhibitor of AKT signaling pathway in tumor cells, it can inhibit invasion by suppressing MMP-2 and MMP-9 expression, it may be a potential anti-metastatic chemotherapeutic agent for the treatment of breast cancer. Excisanin A shows comparable inhibitory effects on the LPS-induced production of NO and PGE2, and activation of NF-kappaB without affecting cell viability.Excisanin A induces apoptosis in colon cancer cell line SW620 as determined by Annexin V staining, the cleavage of caspase-3 and the proteolytic degradation of poly (ADP-ribose) polymerase (PARP) .