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Coronarin A

Product Specifications

CAS Number

119188-33-9

Target

MTOR, S6 Kinase

Related Pathways

PI3K/Akt/mTOR signaling, MAPK

Bioactivity

Coronarin, A, B, C, and D are cytotoxic prinicples from the rhizomes of Hedychium coronarium, Zingiberaceae. Coronarin A exhibits good growth inhibition activities on HUVEC proliferation, it effectively suppresses the growth factor induced tube formation of HUVEC at the concentration of 10 microg/mL. Coronarin A has anti-inflammatory activity, it exhibits potent inhibition (IC50 <6.1708g/mL) against fMLP-induced superoxide production and elastase release.

Smiles

CC1(C)CCC[C@@]2(C)[C@H]1C[C@H](O)C(=C)[C@@H]2\C=C\c1ccoc1

Molecular Formula

C20H28O2

Molecular Weight

300.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Frequently Asked Questions

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