Coronarin A
Product Specifications
CAS Number
119188-33-9
Target
MTOR, S6 Kinase
Related Pathways
PI3K/Akt/mTOR signaling, MAPK
Bioactivity
Coronarin, A, B, C, and D are cytotoxic prinicples from the rhizomes of Hedychium coronarium, Zingiberaceae. Coronarin A exhibits good growth inhibition activities on HUVEC proliferation, it effectively suppresses the growth factor induced tube formation of HUVEC at the concentration of 10 microg/mL. Coronarin A has anti-inflammatory activity, it exhibits potent inhibition (IC50 <6.1708g/mL) against fMLP-induced superoxide production and elastase release.
Smiles
CC1(C)CCC[C@@]2(C)[C@H]1C[C@H](O)C(=C)[C@@H]2\C=C\c1ccoc1
Molecular Formula
C20H28O2
Molecular Weight
300.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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