Pertuzumab (anti-HER2)
Product Specifications
UNSPSC Description
Pertuzumab (anti-HER2), a humanized monoclonal antibody, is a HER2 dimerization inhibitor for the treatment of metastatic HER2-positive breast cancer.
Target Antigen
EGFR
Type
Inhibitory Antibodies
Related Pathways
JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pertuzumab-anti-her2.html
Purity
99.10
Solubility
H2O
Smiles
[Pertuzumab (anti-HER2)]
References & Citations
[1]Nahta R, et al. The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survivalof breast cancer cells. Cancer Res. 2004 Apr 1;64(7):2343-6.|[2]Scheuer W, et al. Strongly enhanced antitumor activity of trastuzumab and pertuzumab combination treatment on HER2-positive human xenograft tumor models. Cancer Res. 2009 Dec 15;69(24):9330-6.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P9912A/Pertuzumab-anti-HER2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P9912A/Pertuzumab-anti-HER2-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
9007-83-4
Available Sizes
Curated Selection
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