Broussonin A
Product Specifications
CAS Number
73731-87-0
Target
NOS|||Akt|||I?B/IKK|||Cholinesterase (ChE) |||NF-?B|||IL Receptor|||ERK
Related Pathways
Neuroscience|||NF-?B|||MAPK|||Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling|||Immunology/Inflammation
Bioactivity
Broussonins A and B, new phytoalexins from diseased paper mulberry. Broussonin A shows estrogenic activity with ligand-binding activity of estrogen receptor, transcriptional activity of estrogen-responsive element-luciferase reporter genes. Broussonin A can significantly inhibit adipocyte differentiation in 3T3-L1 cells as measured fat accumulation using Oil Red O assay; it suppresses lipopolysaccharide (LPS) -stimulated inducible nitric oxide synthase (iNOS) expression at the transcriptional level through modulating NF-κB and down-regulation of the Akt and ERK signaling pathways.
Smiles
COc1ccc(CCCc2ccc(O)cc2)c(O)c1
Molecular Formula
C16H18O3
Molecular Weight
258.317
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
