7-Oxo-beta-sitosterol
Product Specifications
CAS Number
2034-74-4
Target
Apoptosis
Related Pathways
Apoptosis
Bioactivity
7-Oxo-beta-sitosterol (7-Ketositosterol), a phytosterol isolated from the fruit of x giganteus, has anticancer and antitumor activity, inhibits the proliferation of HL-60 acute myeloid leukemia (AML) cells, and stimulates the growth of HL-60 acute myeloid leukemia (AML) cells through the downregulation of the levels of S1P, p-44/42 ERK1/2 and p-NF-?B p65 proteins. -?B p65 protein levels to stimulate ceramide accumulation and apoptosis, and can be used to study breast cancer.
Smiles
C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3=O)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@H](CC[C@H](C(C)C)CC)C)[H])[H]
Molecular Formula
C29H48O2
Molecular Weight
428.69
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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