7,8-Didehydrocimigenol
Product Specifications
CAS Number
150972-72-8
Target
TNF, PPAR, Akt, NF-κB, IκB/IKK, ERK
Related Pathways
Cytoskeletal Signaling, NF-κB, PI3K/Akt/mTOR signaling, Apoptosis, Metabolism, MAPK, DNA Damage/DNA Repair
Bioactivity
7,8-Didehydrocimigenol can be used for the treatment of cardiovascular disorders such as atherosclerosis. It upregulates PPAR-γ in EC inhibits NF-kB activity of TNF-α-activated EC which leads to selective inhibition of VCAM-1 expression.
Smiles
[H][C@]12[C@H](C)C[C@H]3O[C@@]1(O[C@@H]3C(C)(C)O)[C@H](O)[C@@]1(C)C3=CC[C@]4([H])[C@]5(C[C@@]35CC[C@]21C)CC[C@H](O)C4(C)C |t:20|
Molecular Formula
C30H46O5
Molecular Weight
486.693
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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