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5α-Hydroxycostic acid

Product Specifications

CAS Number

132185-83-2

Target

Tie-2, VEGFR

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis

Bioactivity

5α-Hydroxycostic acid, a naturally occurring sesquiterpene, inhibits choroidal neovascularization in rats through dual signaling pathways mediated by VEGF/VEGFR and Ang2/Tie2 (angiopoietin 2), and exhibits anti-inflammatory and anti-angiogenic effects on human breast cancer cells

Smiles

O[C@]12[C@@](C)(CC[C@@H](C(C(O)=O)=C)C1)CCCC2=C

Molecular Formula

C15H22O3

Molecular Weight

250.33

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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