3-Hydroxybakuchiol
Product Specifications
CAS Number
178765-54-3
Target
Glucosidase, Caspase, Apoptosis, ATPase, glycosidase
Related Pathways
Proteases/Proteasome, Membrane transporter/Ion channel, Apoptosis, Metabolism
Bioactivity
3-Hydroxybakuchiol exerts cytotoxic and anti-proliferative effects on the TA3/Ha mouse mammary adenocarcinoma cell line and induces a decrease in the mitochondrial transmembrane potential, the activation of caspase-3, the opening of the mitochondrial permeability transport pore (MPTP) and nuclear DNA fragmentation.3-Hydroxybakuchiol has antitumor activity resulting from interactions with the ETC, a system that is already deficient in cancer cells.
Smiles
C\C(C)=C\CC[C@@](C)(C=C)\C=C\c1ccc(O)c(O)c1
Molecular Formula
C18H24O2
Molecular Weight
272.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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