Homatropine (hydrochloride)

Homatropine hydrochloride is an orally active anticholinergic agent that rapidly dilates pupils and has cycloplegic effects. Homatropine hydrochloride also has antitussive activity. Homatropine hydrochloride can be used in research on eye diseases and coughs[1].

Product Specifications

CAS Number

[637-21-8]

UNSPSC

12352200

Hazard Statement

H302-H315-H319-H335

Target

MAChR

Type

Biochemical Assay Reagents

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/homatropine-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

CN1[C@H]2CC[C@@H]1C[C@H](OC(C(O)C3=CC=CC=C3)=O)C2.Cl

Molecular Formula

C16H22ClNO3

Molecular Weight

311.80

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Gore A, et al. Efficacy assessment of various anticholinergic agents against topical sarin-induced miosis and visual impairment in rats. Toxicol Sci. 2012 Apr;126 (2) :515-24.