16-Hydroxycleroda-3,13-dien-15,16-olide
Product Specifications
CAS Number
141979-19-3
Target
Autophagy, Proteasome
Related Pathways
Autophagy, Proteases/Proteasome, Ubiquitination
Bioactivity
16-Hydroxycleroda-3,13-dien-15,16-olide and prodigiosin are candidates for autophagy inducers that can trigger cell death as a supplement or alternative medicine for cancer therapy. 16-Hydroxycleroda-3,13-dien-15,16-olide regulates the expression of histone-modifying enzymes (PRC2 complex) and induces apoptosis in CML [K562] cells; it also exhibits anti-inflammatory activity, showing promising NO inhibitory activity at 10 ug/mL.
Smiles
C[C@@H]1CC[C@]2(C)[C@H](CCC=C2C)[C@@]1(C)CCC1=CC(=O)OC1O
Molecular Formula
C20H30O3
Molecular Weight
318.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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