1-Decarboxy-3-oxo-ceanothic acid
Product Specifications
CAS Number
214150-74-0
Target
DNA/RNA Synthesis, Apoptosis
Related Pathways
Apoptosis, Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Bioactivity
1-Decarboxy-3-oxo-ceanothic acid exhibits in vitro cytotoxic activity in a human ovarian adenocarcinoma cell line, mediated at least in part by induction of apoptosis. It is cytotoxic against OVCAR-3 and HeLa cancer cell lines with IC50 values of 2.8 and 6.6 microg/mL, respectively, and has an IC50 of 11.3 microg/mL against normal cell line FS-5.
Smiles
[H][C@@]12CC[C@]3(C)[C@]([H])(CC[C@]4([H])[C@@]5([H])[C@@H](CC[C@@]5(CC[C@@]34C)C(O)=O)C(C)=C)[C@@]1(C)CC(=O)C2(C)C
Molecular Formula
C29H44O3
Molecular Weight
440.668
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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