Sophoflavescenol
Product Specifications
CAS Number
216450-65-6
Target
Beta-Secretase, Cholinesterase (ChE), BACE, PDE, AChR
Related Pathways
Metabolism, Neuroscience
Purity
0.9965
Bioactivity
Sophoflavescenol is a mixed inhibitor of PDE5 with a K (i) value of 0.005 microM. Sophoflavescenol has antioxidant, anti-inflammatory, and apoptotic effects , these effects might contribute to the antitumor activity without severe side effects. Sophoflavescenol exerts notable anti-inflammatory activity by inhibiting nitric oxide generation and tert-butylhydroperoxide-induced ROS generation rather than inhibiting nuclear factor kappa B activation in RAW 264.7 cells.
Smiles
COc1cc(O)c(CC=C(C)C)c2oc(c(O)c(=O)c12)-c1ccc(O)cc1
Molecular Formula
C21H20O6
Molecular Weight
368.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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