Physalin B
Product Specifications
CAS Number
23133-56-4
Target
Autophagy, NOD, Apoptosis, Akt, NF-κB, Nrf2, PI3K
Related Pathways
Autophagy, Apoptosis, PI3K/Akt/mTOR signaling, NF-κB, Immunology/Inflammation, Cytoskeletal Signaling
Purity
0.984
Bioactivity
Physalin B is one of the major active compounds from the Solanaceae family of plants and has a wide range of biological activities for the treatment of inflammatory eczema and herpes, among other diseases.Physalin B ameliorates lipopolysaccharide-induced inflammatory response due to acute lung injury by inhibiting NF-κB and NLRP3 through activation of the PI3K/Akt pathway.Physalin B inhibits PDGF-BB-induced VSMC proliferation and migration and phenotypic transformation through activation of the Nrf2 pathway. Physalin B inhibits PDGF-BB-induced VSMC proliferation, migration and phenotypic transformation through activation of the Nrf2 pathway.Physalin B exerts antitumor activity by inhibiting LAP2α-HDAC1-mediated deacetylation of glioma-associated oncogene 1 and hepatic stellate cell activation.
Smiles
[H][C@@]12C(=O)[C@]34O[C@]11[C@@](C)(OC(=O)[C@@]1(O)CC[C@@]1([H])[C@@]3([H])CC=C3CC=CC(=O)[C@]13C)[C@H]1C[C@]2(C)[C@@]([H])(CO4)C(=O)O1
Molecular Formula
C28H30O9
Molecular Weight
510.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
126304-ML550 100 µL
EMILIN1 (DKFZp586M121, EMILIN-1, Elastin Microfibril Interface-located Protein 1, Elastin Microfibril Interfacer 1, EMI) (MaxLight 550)
Sign In for Pricing
View Details