Isocryptotanshinone
Product Specifications
CAS Number
22550-15-8
Target
STAT|||JNK|||ERK
Related Pathways
JAK/STAT signaling|||MAPK|||Stem Cells
Bioactivity
Isocryptotanshinone inhibits protein tyrosine phosphatase 1B (PTP1B) activity with 50% inhibitory concentration values of 56.1±6.3 ?M, PTP1B acts as a negative regulator of insulin signaling, and selective inhibition of PTP1B has served as a potential drug target for the treatment of type 2 diabetes.
Smiles
O=C1C=2C3=C(C=CC2C(=O)C4=C1OC[C@H]4C)C(C)(C)CCC3
Molecular Formula
C19H20O3
Molecular Weight
296.36
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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