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Garcinone D

Product Specifications

CAS Number

107390-08-9

Target

STAT, Reactive Oxygen Species, ROS, Nrf2

Related Pathways

Immunology/Inflammation, Stem Cells, JAK/STAT signaling, NF-κB, Metabolism

Purity

0.9996

Bioactivity

Garcinone D shows significant cytotoxicity against the CEM-SS cell line, with IC (50) value of 3.2 microg/ml; it exhibits dose-dependent enzyme-based microsomal aromatase inhibitory activity. Garcinone D inhibits p65 activation with IC50 values of 3.2 microM.

Smiles

COc1c(O)cc2oc3cc(O)c(CC=C(C)C)c(O)c3c(=O)c2c1CCC(C)(C)O

Molecular Formula

C24H28O7

Molecular Weight

428.47

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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