Eriocalyxin B
Product Specifications
CAS Number
84745-95-9
Target
FABP, mTOR, STAT, Autophagy, NF-κB, Akt, Apoptosis, cAMP, ROS, PPAR, CDK
Related Pathways
Immunology/Inflammation, GPCR/G Protein, PI3K/Akt/mTOR signaling, NF-κB, Cell Cycle/Checkpoint, Metabolism, JAK/STAT signaling, Stem Cells, Autophagy, Apoptosis, Cytoskeletal Signaling, DNA Damage/DNA Repair
Purity
0.9984
Bioactivity
Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase- and p53-dependent pathways, should be considered a candidate for pancreatic cancer treatment; it is a specific inhibitor of STAT3, it directly targets STAT3 through a covalent linkage to inhibit the phosphorylation and activation of STAT3 and induces apoptosis of STAT3-dependent tumor cells.
Smiles
[H][C@@]12C[C@@]3(C(=O)C1=C)[C@@]([H])(CC2)[C@@]12CO[C@]3(O)[C@@H](O)[C@]1([H])C(C)(C)C=CC2=O
Molecular Formula
C20H24O5
Molecular Weight
344.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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