Eriocalyxin B
Product Specifications
CAS Number
84745-95-9
Target
FABP|||mTOR|||STAT|||Autophagy|||NF-?B|||Akt|||Apoptosis|||cAMP|||ROS|||PPAR|||CDK
Related Pathways
Immunology/Inflammation|||GPCR/G Protein|||PI3K/Akt/mTOR signaling|||NF-?B|||Cell Cycle/Checkpoint|||Metabolism|||JAK/STAT signaling|||Stem Cells|||Autophagy|||Apoptosis|||Cytoskeletal Signaling|||DNA Damage/DNA Repair
Purity
0.9984
Bioactivity
Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase- and p53-dependent pathways, should be considered a candidate for pancreatic cancer treatment; it is a specific inhibitor of STAT3, it directly targets STAT3 through a covalent linkage to inhibit the phosphorylation and activation of STAT3 and induces apoptosis of STAT3-dependent tumor cells.
Smiles
[H][C@@]12C[C@@]3(C(=O)C1=C)[C@@]([H])(CC2)[C@@]12CO[C@]3(O)[C@@H](O)[C@]1([H])C(C)(C)C=CC2=O
Molecular Formula
C20H24O5
Molecular Weight
344.4
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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