Damnacanthal
Product Specifications
CAS Number
477-84-9
Target
Antifungal, Apoptosis, LIM Kinase, Src
Related Pathways
Apoptosis, Microbiology/Virology, Cell Cycle/Checkpoint, Angiogenesis, Tyrosine Kinase/Adaptors
Bioactivity
Damnacanthal is a natural anthraquinone compound with potential anticancer, anti-inflammatory, antioxidant, anti-malarial, and antiviral effects.Damnacanthal inhibits a variety of protein kinases such as LIMK1 (IC50=0.8 μM), LIMK2 (IC50=1.5 μM), and Lck (IC50=17 nM), and inhibits the growth of human hepatocellular carcinoma (SKHep-1) and human breast cancer (MCF-7) cells.
Smiles
O=CC1=C(O)C=C2C(=O)C=3C=CC=CC3C(=O)C2=C1OC
Molecular Formula
C16H10O5
Molecular Weight
282.25
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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