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Damnacanthal

Product Specifications

CAS Number

477-84-9

Target

Antifungal|||Apoptosis|||LIM Kinase|||Src

Related Pathways

Apoptosis|||Microbiology/Virology|||Cell Cycle/Checkpoint|||Angiogenesis|||Tyrosine Kinase/Adaptors

Bioactivity

Damnacanthal is a natural anthraquinone compound with potential anticancer, anti-inflammatory, antioxidant, anti-malarial, and antiviral effects.Damnacanthal inhibits a variety of protein kinases such as LIMK1 (IC50=0.8 ?M), LIMK2 (IC50=1.5 ?M), and Lck (IC50=17 nM), and inhibits the growth of human hepatocellular carcinoma (SKHep-1) and human breast cancer (MCF-7) cells.

Smiles

O=CC1=C(O)C=C2C(=O)C=3C=CC=CC3C(=O)C2=C1OC

Molecular Formula

C16H10O5

Molecular Weight

282.25

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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