Cucurbitacin A
Product Specifications
CAS Number
6040-19-3
Target
ROCK
Related Pathways
Cytoskeletal Signaling, Stem Cells, Cell Cycle/Checkpoint
Bioactivity
Cucurbitacin I, cytotoxic triterpenoid sterols isolated from plants, elicits the formation of actin/phospho-myosin II co-aggregates by stimulation of the RhoA/ROCK pathway and inhibition of LIM-Kinase.
Smiles
[H][C@@]12C[C@H](O)C(=O)C(C)(C)C1=CC[C@@]1([H])[C@]3(C)C[C@@H](O)[C@H]([C@@](C)(O)C(=O)\C=C\C(C)(C)OC(C)=O)[C@@]3(C)CC(=O)[C@@]21CO
Molecular Formula
C32H46O9
Molecular Weight
574.7
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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