Chicanine
Product Specifications
CAS Number
78919-28-5
Target
ERK, p38 MAPK, IκB/IKK
Related Pathways
MAPK, NF-κB
Bioactivity
Chicanine is a natural lignan that inhibits LPS-induced phosphorylation of p38 MAPK, ERK1/2, and IκB-α in macrophages, exhibiting anti-inflammatory activity.
Smiles
C[C@H]1[C@@H](O[C@H]([C@H]1C)C2=CC(OC)=C(O)C=C2)C=3C=C4C(=CC3)OCO4
Molecular Formula
C20H22O5
Molecular Weight
342.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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