4'-Hydroxywogonin
Product Specifications
CAS Number
57096-02-3
Target
ROS, Interleukin, PI3K, MAPK, Bcl-2 Family, Akt, NF-κB, Caspase, Apoptosis, p38 MAPK, Reactive Oxygen Species, IL Receptor, IκB/IKK, TNF
Related Pathways
Cytoskeletal Signaling, NF-κB, MAPK, Metabolism, Proteases/Proteasome, PI3K/Akt/mTOR signaling, Immunology/Inflammation, Apoptosis
Bioactivity
4'-Hydroxywogonin (8-Methoxyapigenin), a natural flavonoid with anti-inflammatory properties, reduced the production of pro-inflammatory cytokines (e.g., TNF-α, IL-6, and IL-1β), inhibited the TAK1/IKK/NF-κB signaling pathway, and reduced the phosphorylation of MAPKs and the PI3/Akt signaling pathway.
Smiles
O=C1C=C(OC=2C(OC)=C(O)C=C(O)C12)C=3C=CC(O)=CC3
Molecular Formula
C16H12O6
Molecular Weight
300.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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