Epimagnolin B
Product Specifications
CAS Number
1134188-26-3
Target
Prostaglandin Receptor, NF-κB, NO Synthase
Related Pathways
Immunology/Inflammation, NF-κB, GPCR/G Protein
Bioactivity
Epimagnolin B has anti-inflammatory activity, it can inhibit the production of NO and PGE (2) and the expression of respective enzyme iNOS and COX-2 through the suppression of I-kappaB-alpha degradation and nuclear translocation of p65 subunit of NF-kappaB. It also exhibits antiallergic effects without affecting the viability of bone marrow-derived mast cells.
Smiles
[H][C@@]12CO[C@H](c3cc(OC)c(OC)c(OC)c3)[C@]1([H])CO[C@H]2c1cc(OC)cc(OC)c1
Molecular Formula
C23H28O7
Molecular Weight
416.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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