7-Hydroxyaristolochic acid A
Product Specifications
CAS Number
79185-75-4
Target
DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Purity
0.9947
Bioactivity
7-Hydroxyaristolochic acid A is a natural derivative of aristolochic acid. Aristolochic acid is nephrotoxic and carcinogenic, inhibits APE1/Nrf2/HO-1 axis-induced oxidative stress and apoptosis leading to nephrotoxicity, and induces apoptosis in NRK-52E cells via COX-2 and PGE2.
Smiles
O=C(C1=CC2=C(C3=C4C=CC(O)=C(C4=CC([N+]([O-])=O)=C13)OC)OCO2)O
Molecular Formula
C17H11NO8
Molecular Weight
357.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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