Dehydroglyasperin D
Product Specifications
CAS Number
517885-72-2
Target
P38 MAPK|||Reductase|||Akt|||Prostaglandin Receptor|||GSK-3|||JNK|||COX|||PI3K|||DNA/RNA Synthesis|||ROS
Related Pathways
DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling|||Cell Cycle/Checkpoint|||Endocrinology/Hormones|||GPCR/G Protein|||Metabolism|||Neuroscience|||Immunology/Inflammation|||Cytoskeletal Signaling|||Stem Cells|||MAPK
Bioactivity
Dehydroglyasperin D exhibits anticancer, anti-inflammatory, anti-obesity, antioxidant and anti-aldose reductase effects, it inhibits the proliferation of HT-29 human colorectal cancer cells through direct interaction with phosphatidylinositol 3-kinase; it also mediates suppression of both COX-2 expression and the MLK3 signalling pathway through direct binding and inhibition of MLK3. Dehydroglyasperin D shows strong ferric reducing activities and effectively scavenged DPPH, ABTS (+), and singlet oxygen radicals.
Smiles
O(C)C1=C2C(=CC(OC)=C1CC=C(C)C)OCC(=C2)C3=C(O)C=C(O)C=C3
Molecular Formula
C22H24O5
Molecular Weight
368.42
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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