Pulegone

Product Specifications

CAS Number

89-82-7

Target

COX|||JNK|||Antifungal|||NF-?B|||p38 MAPK|||Calcium Channel|||Endogenous Metabolite|||Nrf2|||ROS|||PERK|||NO Synthase|||TRP/TRPV Channel|||Antibacterial

Related Pathways

Apoptosis|||MAPK|||Neuroscience|||Membrane transporter/Ion channel|||NF-?B|||Metabolism|||Immunology/Inflammation|||Microbiology/Virology

Purity

0.9874

Bioactivity

1. Pulegone ((+) -Pulegone) has cytotoxicity followed by regenerative cell proliferation is the MOA for Pulegone-induced urothelial tumors in female rats. 2. Pulegone induces a verapamil-sensitive psychostimulant effect that appears to independ on the opening of L-type calcium channels. 3. Pulegone has negative reinforcing properties and seems to possess anxiolytic-like actions unrelated to the benzodiazepine site of the ?-aminobutyric acid type A (GABAA) receptor.