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EZM0414

Product Specifications

CAS Number

2411748-50-8

Target

Histone Methyltransferase

Related Pathways

Chromatin/Epigenetic

Purity

0.9958

Bioactivity

EZM0414 is a potent and selective, orally bioavailable inhibitor of SETD2 with an IC50 of 18 nM in biochemical assays and 34 nM in cellular assays, potentially useful for researching relapsed or refractory multiple myeloma and diffuse large B-cell lymphoma [1].

Smiles

[H][C@@]1(CCC[C@H](C1)NC(=O)c1cc2c(F)ccc(C)c2[nH]1)N1CCN(CC1)C(C)=O

Molecular Formula

C22H29FN4O2

Molecular Weight

400.49

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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