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STING agonist-12

Product Specifications

CAS Number

2259624-71-8

Target

STING

Related Pathways

Immunology/Inflammation

Purity

0.9829

Bioactivity

STING activator Compound 53 based on an oxindole core structure demonstrated robust on-target functional activation of STING (human EC50 185 nM) in immortalised and primary cells and a cytokine induction fingerprint consistent with STING activation.

Smiles

CC1(C)C(=O)N(Cc2c(F)cccc2Cl)c2cc(ccc12)C(=O)NCc1c(F)cc(F)cc1F

Molecular Formula

C25H19ClF4N2O2

Molecular Weight

490.88

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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