(E) -SI-2
Product Specifications
CAS Number
380537-35-9
Target
Others
Related Pathways
Others
Purity
0.998
Bioactivity
(E) -SI-2 is a potent small-molecule inhibitor of steroid receptor coactivator-3 (SRC-3 or AIB1) that can selectively inhibit the intrinsic transcriptional activities of SRC-3, also inhibits SRC-1 and SRC-2. It selectively reduces cellular protein levels of SRC-3, but not that of CARM-1, blocks MDA-MB-468 cell growth with an IC50 value of 3.4 nM, but spares normal cells.
Smiles
CN1C=2C(N=C1N/N=C(\C)/C3=CC=CC=N3)=CC=CC2
Molecular Formula
C15H15N5
Molecular Weight
265.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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