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Opiranserin hydrochloride

Product Specifications

CAS Number

1440796-75-7

Target

GlyT, 5-HT Receptor, P2X Receptor

Related Pathways

Neuroscience, GPCR/G Protein, Membrane transporter/Ion channel

Purity

0.9933

Bioactivity

Opiranserin (VVZ-149) hydrochloride is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μM, respectively. It shows antagonistic activity on rP2X3 (IC50=0.87 μM) . It is development as an injectable agent for the treatment of postoperative pain.

Smiles

Cl.CCCCOc1c(OC)cc(cc1OC)C(=O)NCC1(CCOCC1)N(C)C

Molecular Formula

C21H35ClN2O5

Molecular Weight

430.97

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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