MKC-1
Product Specifications
CAS Number
125313-92-0
Target
Microtubule Associated, Akt, Apoptosis, mTOR
Related Pathways
Cytoskeletal Signaling, Apoptosis, PI3K/Akt/mTOR signaling
Purity
0.9985
Bioactivity
MKC-1 (Ro-31-7453) is an orally bioavailable small-molecule bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking mitotic spindle formation, which may result in apoptosis and tumor cell death.
Smiles
Cn1cc(C2=C(C(=O)NC2=O)c2cn(C)c3cc(ccc23)[N+]([O-])=O)c2ccccc12
Molecular Formula
C22H16N4O4
Molecular Weight
400.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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