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MKC-1

Product Specifications

CAS Number

125313-92-0

Target

Microtubule Associated, Akt, Apoptosis, mTOR

Related Pathways

Cytoskeletal Signaling, Apoptosis, PI3K/Akt/mTOR signaling

Purity

0.9985

Bioactivity

MKC-1 (Ro-31-7453) is an orally bioavailable small-molecule bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking mitotic spindle formation, which may result in apoptosis and tumor cell death.

Smiles

Cn1cc(C2=C(C(=O)NC2=O)c2cn(C)c3cc(ccc23)[N+]([O-])=O)c2ccccc12

Molecular Formula

C22H16N4O4

Molecular Weight

400.39

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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