JAK3/BTK-IN-1
Product Specifications
CAS Number
2674036-91-8
Target
JAK, BTK
Related Pathways
Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Angiogenesis, Stem Cells, JAK/STAT signaling
Purity
0.9789
Bioactivity
JAK3/ BTk-in-1 is a dual JAK3/BTK inhibitor that specifically targets and inhibits Janus kinase 3 (JAK3) and Bruton's tyrosine kinase (BTK), two important targets in autoimmune diseases. JAK3/ BTk-in-1 simultaneously inhibited the BTK/JAK3 signaling pathway, showing a synergistic effect. JAK3/ BTK-in-1 is a potential compound for the treatment of immune-related diseases, such as autoimmune diseases, certain types of cancer (including lymphoma and leukemia), and other diseases that may be characterized by an unbalanced immune response.
Smiles
N(C1=C2C(=CNC2=NC(NC3=CN(CC)N=C3)=N1)C4=CC=CC=C4)[C@H]5CN(C(C=C)=O)CCC5
Molecular Formula
C25H28N8O
Molecular Weight
456.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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