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INE963

Product Specifications

CAS Number

2640567-43-5

Target

Haspin Kinase, Parasite, FLT, Others

Related Pathways

Tyrosine Kinase/Adaptors, Others, Angiogenesis, Cell Cycle/Checkpoint, Microbiology/Virology

Purity

0.9945

Bioactivity

INE963 demonstrates potent cellular activity against Pf 3D7 (EC50 = 6 nM) and achieves "artemisinin-like" kill kinetics in vitro with a parasite clearance time of <24 h. INE963 is also potent against P. falciparum and P. vivax clinical isolates from Brazil and Uganda with EC50's ranging from 0.01 to 7.0 nM

Smiles

COc1nc(ccc1-c1cnc2sc(nn12)N1CCC(O)(CN)CC1)C(C)C

Molecular Formula

C19H26N6O2S

Molecular Weight

402.51

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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