VY-3-135
Product Specifications
CAS Number
1824637-41-3
Target
Others, Acetyl-CoA Carboxylase, Fatty Acid Synthase
Related Pathways
Others, Metabolism
Purity
0.9979
Bioactivity
VY-3-135 is an orally active, stable and specific acetyl-CoA synthetase 2 (ACSS2) inhibitor with IC50 of 44 nM, showing no inhibitory activity against recombinant human ACSS1 or ACSS3. VY-3-135 can effectively inhibit ACSS2-dependent fatty acid metabolism but has no effect on gene expression in tumors.
Smiles
CCn1c(nc2ccc(cc12)C(=O)NC[C@@H](C)O)C(O)(c1ccccc1)c1ccccc1
Molecular Formula
C26H27N3O3
Molecular Weight
429.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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