DB2313

Product Specifications

CAS Number

2170606-74-1

Target

Apoptosis

Related Pathways

Apoptosis

Purity

0.9973

Bioactivity

DB2313 (Carboximidamide) is a potent transcription factor PU.1 inhibitor, IC50=14 nM. DB2313 disrupts the interaction of PU.1 with target gene promoters. DB2313 induces apoptosis of acute myeloid leukemia (AML) cells, and has anticancer effects

Smiles

CC(C)NC(=N)c1ccc2nc([nH]c2c1)-c1ccc(OCc2cccc(COc3ccc(cc3)-c3nc4ccc(cc4[nH]3)C(=N)NC(C)C)c2F)cc1

Molecular Formula

C42H41FN8O2

Molecular Weight

708.83

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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